| STUDIES
INVOLVING THE SKIN
Test 1
 To determine the amount of MSM needed to
produce a desired effect, a series of tests on healthy skin of human
subjects were performed. Eleven separate compositions were formed
containing different amounts of MSM. As a solvent, each composition
included a liquid comprising equal amounts of water and ethanol.
Compositions were applied daily to separate subjects. Softness and
smoothness were improved after two to three weeks when a 1 to 5 %
MSM solution was applied. Rapid improvement (within a week) in skin
softness and smoothness were observed when the solution contained 5
or more % of MSM.
Test 2
A gel containing 6 % by weight MSM was applied to the skin of
subjects having a variety of problem skin conditions. In none of
these applications did the subjects experience instantaneous
discomfort of the type frequently encountered when medical
preparations were applied. In a number of instances the gel was
soothing to the effected skin and provided a protective coating for
the affected area.
Test 3
Fifty human subjects applied a gel containing 6 % by weight MSM to
the skin of the right hand and right foot for three weeks twice
daily. The subjects were requested to abstain from using other
cosmetic preparations during the test period. After one week, the
evaluators noted a substantial improvement in skin softness,
smoothness and comfort. Seven of the subjects continued to apply the
formulation for a second week. At the end of this period, further
improvement in softness, smoothness and comfort were observed.
Test 4
MSM was added to hydrolyzed collagen representative of the collagen
found in the external layer of the skin which hardens with
dehydration. Five aqueous solutions of MSM were prepared containing
2, 4, 6, 8 and 10 % by weight of MSM. Each of the solutions was
heated and combined with a sample of modified collagen at a weight
ratio of nine to one. Normally, collagen combined with heated water
will swell and form chemical bonds (cross linking) to form a gel.
However, no gelation occurred in the mixtures containing 8 to 10
weight percent of MSM solution.
STUDY INVOLVING MSM
GEL USED WITH SHAVING
Subjects applied a 6% by weight MSM gel a few minutes before shaving
with a razor blade and using a commercial shaving cream. The
application of the gel made for a more comfortable, smoother and
cleaner shave than if the commercial shaving cream was used without
the MSM gel. Another observation was, that the skin resistance and
drag of the razor was reduced. When MSM gel was applied to the skin
of the legs of several women, it was observed that leg hair could
more easily be removed by shaving, even without applying a
commercial shaving cream overcoat. In all instances, use of the
formulation left the skin feeling softer and smoother.
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